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Naresh Kuthala Research Scientist

Taiwan Naresh Kuthala Naresh-Kuthala-CV-2019-singapore.pdf
Boron neutron capture therapycancer therapynanomaterials synthesis & characterizationPhotodynamic & photo thermal therapySEM and TEM operation & characterization
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Objective

Seeking a R&D research scientist/Research scientist position to utilize my skills and assists my growth and facilitates more exposure towards emerging strategies.

 

Work Experience

Ø  09/2018~ To Date: Postdoctoral Research fellow, Department Of Chemistry, National Tsing Hua University, Taiwan.

Project Title: Nanomaterial mediated photodynamic therapy to boost immune response for eradication of tumors.

Educational Background

Ø  2012-2018: Doctoral degree (Ph.D.) in Chemistry at National Tsing Hua University, Taiwan.

Thesis title: Nanomaterial-mediated boron neutrons capture therapy and photodynamic therapy for the destruction of tumors.

Qualifying examinations cleared during Ph.D.: 1) Analytical Chemistry (Chemical separation) 2) Bio-chemistry 3) Materials chemistry.

Courses under taken: 1) Analytical techniques for materials chemistry 2) Trace analysis 3) Analytical mass spectrometry 4) Nanomaterials chemistry 5) Transmission electron microscopy.

Ø  2011-2012: Worked as a Teaching-cum-Research Assistant at IIT-Chennai, India.

Ø  2009-2011: Masters degree in Chemistry from Indian Institute of Technology (IIT)-Chennai, India.

Project title: Preparation and characterization of high surface area g-Alumina catalyst.

Ø  2007-2009: Worked as a high school teacher in Telangana, India.

Ø  2004-2007: Bachelor Degree in Chemistry, Mathematics and Physics from Osmania University, India.

Research Interests

Ø  Design of novel multi-functional nanostructures for various biomedical applications, related to early detection (MRI, fluorescence imaging, photoacoustic imaging) and cancer therapy (drug delivery BNCT and phototherapies).

Ø  Photochemistry  of  various  metal  nanoparticles  and  their  localized  surface  plasmon  resonances (LSPRs).

Ø  Fabrication of 10B enriched nanostructures for optical imaging and Boron and Gadolinium neutron capture therapy of various cancer.

 

Honors and awards

Ø  Successful recipient of Tsing Hua Scholarship for three consecutive years (2012-2015) during my doctoral study.

Ø  Recipient of CTCI scholarship award in honor of outstanding performance award for excellence in research (16th Dec 2017) at Taiwan

Ø  Recipient of research excellence award of BenQ materials corporation scholarship-2017 (25th Dec 2017) at Taiwan

 

Conferences Attended

Ø  Attended Asia and Oceania Conference on Photobiology-2015, held at Taipei, Taiwan.

Ø  Attended 3rd international conference on ‘Single molecule/nanoparticle spectroscopy and imaging’, held at NCTU, Taiwan in 2014.

Ø  Attended 20th National Symposium on catalysis-2010, at IIT-Chennai, India

Ø  Poster presentation at NTHU-KAIST-KYOTO junior chemist symposium-2018 at NTHU-Taiwan

Scientific Skills Expertise

Ø  Materials Synthesis: Experienced in preparing variety of nanomaterials, such as gold and silver nanoparticles, metal-filled carbon nanoparticles, and boron based nanomaterials.

Ø  Surface  modifications:  Experienced  in  doing  surface  modifications  to  nanoparticles,  such  as, targeting ligands, peptides and antibodies.

Ø  Materials Characterization: SEM, TEM, TGA, UV-Vis-NIR, Raman, DLS and Single Photon Counter (Steady state measurements)

Ø  Biology Experiments: Experience in handling mammalian cell cultures, Drug Delivery and Photodynamic Therapy in Cancer Cells, Flow Cytometry FACS Calibur, Fluorescence Microscopy, Confocal Laser Scanning Microscopy (LSM 700), Boron neutron capture therapy in cancer cells and invivo.

Ø  In vivo Experiments: Experience in handling mouse animal models (Intravenous administration of nanocarrier/drugs, IVIS imaging and immunological / histological tissue examination), Boron Neutron Capture Therapy, Photodynamic, Photo Thermal and Immunotherapy mice models.

Technical Background

Ø  Operating Systems: DOS, WINDOWS, MS OFFICE

Ø  Softwares: Origin 8, Graph Pad Prism, Flow Jo, Win MDI 2.9, Chem Biodraw, Image J, Image pro plus and Adobe Photoshop.

Ø  Scientific Search: Well familiar with literature searches in various online data bases, such as, ISI Web of Science, SciFinder and Scopus.

Scientific Journal Publications

1)      Naresh Kuthala, Raviraj Vankayala, Yi-Nan Li, Chi-Shiun Chiang, Kuo Chu Hwang*, ‘Engineering Novel Targeted Boron-10-Enriched Theranostic Nanomedicine to Combat against Murine Brain Tumors via MR Imaging-Guided Boron Neutron Capture Therapy, Advanced Materials (2017). (SCI IF = 25.809)

2)      Naresh  Kuthala,  Raviraj Vankayala,  Chi-Shiun  Chiang,  Kuo  Chu  Hwang,  “A  Smart  Lanthanum Hexaboride Based Theranostic Nanoplatform for Combating Hypoxia in Multidrug Resistant Tumors via NIR  Light  Activated  Photodynamic  Therapy  in  the  Third  Biological  Window”,  Manuscript  in preparation.

3)      Raviraj Vankayala, Naresh Kuthala, Chi-Shiun Chiang, Kuo Chu Hwang*, “Metal Nanoparticles as a New Class of Near Infra-red Light Activatable Photocatalysts for Degradation of Organic Dyes and Inactivation of Bacteria”, Manuscript in preparation.

Karthik Nuthalapati, Raviraj Vankayala, Naresh Kuthala, Chi-Shiun Chiang, Kuo Chu Hwang*, “Engineering New Generation of Near Infrared Light Activatable Photocatalysts as Targeted Nanomaterial-Mediated Phototherapeutic Agents for Treating Drug Resistant Tumors”, Manuscript in preparation.

Education

2012~2018 Ph.D. at National Tsing Hua University-Hsinchu, Taiwan
2009~2011 Master of Science in Chemistry at Indian Institute Of Technology-Madras, India

Experience

2018~2019 Postdoctoral Research Assistant at National Tsing Hua University-Hsinchu, Taiwan
2019~ till date Postdoctoral Research Fellow at National Tsing Hua University-Hsinchu, Taiwan